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Invasive lung adenocarcinoma mimicking chronic infection in HIV

Imaging findings

Chest CT shows a massive right upper lobe mass causing destruction of the adjacent second, third, and fourth ribs, in a patient with HIV/AIDS who had a history of Pneumocystis jirovecii pneumonia in the same lobe 4 years prior.

Key takeaways

In patients with HIV, lung cancer can occur at a younger age and behave more aggressively. Pre-existing scars from infections (such as PCP) can mask developing adenocarcinoma, leading to delayed diagnosis.

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