CTICasesGranulomatosis with polyangiitis (GPA) presenting as rapidly progressive nodules
Imaging findings
CT demonstrates multiple smooth-margined, necrotic, peripheral lung nodules, some with cavitation, which showed rapid growth and increased wall thickness over a 2-week interval. PR3-ANCA serology was positive.
Key takeaways
Pulmonary nodules and masses are the most common manifestation of GPA. They can have smooth or shaggy walls, frequently cavitate, and can enlarge or evolve very rapidly, mimicking septic emboli or metastases.
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