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High-grade liposarcoma of the pectoralis muscle

Imaging findings

CT shows a large, predominantly fatty intramuscular mass in the pectoralis major muscle containing nodular, ground-glass, and fibrotic non-adipose soft-tissue components.

Key takeaways

While simple lipomas are common and benign, the presence of thick septa, nodular soft-tissue components, or non-lipomatous ground-glass areas within a fatty muscle mass should raise concern for liposarcoma.

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