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Primary aortic angiosarcoma

Imaging findings

CT shows a lobulated, nodular intraluminal mass in the descending aorta causing narrowing and rapidly progressing to complete occlusion over 2 months. PET/CT shows intense FDG uptake and multiple lytic bone metastases.

Key takeaways

Primary aortic angiosarcoma is a rare, extremely aggressive vascular malignancy. It typically presents as a lobulated intraluminal filling defect that can rapidly enlarge and cause aortic occlusion or distal embolism, and carries a very poor prognosis.

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