CTICasesFOLFIRI-Induced Lung Toxicity
Imaging findings
CT chest in a patient undergoing FOLFIRI chemotherapy for colon cancer shows bilateral, diffuse ground-glass opacities, dilated airways, and small pleural effusions, consistent with an organizing pneumonia or acute lung injury pattern.
Key takeaways
Chemotherapy regimens can cause drug-induced lung toxicity. FOLFIRI (folinic acid, fluorouracil, irinotecan) is a rare cause of drug-induced pneumonitis. Radiographic findings typically show an organizing pneumonia or DAD pattern, and treatment involves discontinuation of the offending agent and steroids.
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