CTICasesLimb Ischemia-Induced Organizing Lung Injury
Imaging findings
CT chest in a patient presenting with severe left lower extremity arterial occlusion (rhabdomyolysis and myonecrosis) shows symmetric, bilateral peripheral ground-glass opacities and areas of consolidation. The patient was asymptomatic from a respiratory standpoint and had negative COVID-19 PCR testing.
Key takeaways
Acute extremity ischemia and subsequent reperfusion can cause systemic inflammatory response syndrome (SIRS). Reperfusion injury triggers pulmonary neutrophil sequestration and alveolar capillary membrane damage, presenting radiographically as bilateral peripheral ground-glass opacities mimicking organizing pneumonia or viral infection.
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