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Granulomatosis with polyangiitis (GPA) with tracheobronchial and parenchymal involvement

Imaging findings

MR angiogram and CT show multiple cavitating, necrotic pulmonary nodules and masses, accompanied by circumferential subglottic tracheal, lower tracheal, and bronchial wall thickening and narrowing. ANCA was positive.

Key takeaways

GPA (formerly Wegener's) can present with both parenchymal nodules/cavities and tracheobronchial involvement (typically subglottic stenosis). Gated MRA or CTA is useful to evaluate the airway stenosis and necrotic masses in patients with renal impairment.

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