Granulomatosis with polyangiitis (GPA) with tracheobronchial and parenchymal involvement
Imaging findings
MR angiogram and CT show multiple cavitating, necrotic pulmonary nodules and masses, accompanied by circumferential subglottic tracheal, lower tracheal, and bronchial wall thickening and narrowing. ANCA was positive.
Key takeaways
GPA (formerly Wegener's) can present with both parenchymal nodules/cavities and tracheobronchial involvement (typically subglottic stenosis). Gated MRA or CTA is useful to evaluate the airway stenosis and necrotic masses in patients with renal impairment.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Typical bronchial carcinoid tumor causing recurrent pneumoniaNeoplastic
- Ossified pleural metastases from osteosarcomaNeoplastic
- Phosphaturic mesenchymal tumor causing tumor-induced osteomalaciaNeoplastic
- Progression of fibrotic hypersensitivity pneumonitisExposure
- Progression and acute exacerbation of scleroderma-associated NSIPAutoimmune
- Recurrent acute farmers lung (hypersensitivity pneumonitis)Exposure
- EVALI presenting as acute organizing pneumoniaExposure
See all cases from August 2, 2019 →
Related Autoimmune cases
- Ruptured rheumatoid lung nodules causing hydropneumothorax
- Aortitis in systemic sarcoidosis
- Coronary peri-arteritis in IgG4-related systemic disease
- Granulomatous-lymphocytic interstitial lung disease (GLILD) in CVID
- Sarcoidosis involving the intrapulmonary lymphoid tissue (IPL)
- Flow-related pseudo-pulmonary embolism (black smoke artifact) in scleroderma