CTICasesCystic Pulmonary Adenocarcinoma
Imaging findings
Chest CT in a smoker demonstrates a very bubbly, predominantly cystic lung lesion with a thin, irregular solid outer rind. Retrospective review of chest radiographs from three years prior shows a subtle area of increased opacity that had been slowly growing, which was subsequently biopsy-proven to be adenocarcinoma.
Key takeaways
Cystic pulmonary adenocarcinomas present as bubbly or cystic spaces with thin solid walls rather than typical solid or ground-glass nodules. These lesions are highly indolent, can persist or slowly grow over years, and are easily missed on radiographs or misclassified under standard lung cancer screening algorithms like Lung-RADS.
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