Cystic Pneumocystis jirovecii Pneumonia (PJP) with Bilateral Spontaneous Pneumothoraces
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Imaging findings
Chest CT shows numerous, bizarre, thick- and thin-walled parenchymal cysts (pneumatoceles) distributed throughout both lungs, some of which directly abut the pleural surface, with a relative paucity of classic ground-glass opacity. Serial imaging shows the development of bilateral spontaneous pneumothoraces and pneumomediastinum.
Key takeaways
While ground-glass opacity is the classic presentation of PJP, some patients present with a highly atypical, predominantly cystic pattern. Rupture of these subpleural pneumatoceles often leads to single or bilateral spontaneous pneumothoraces, a well-recognized and potentially life-threatening complication of PJP in HIV/AIDS patients.
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