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Cytomegalovirus (CMV) Pneumonia with Organizing Pneumonia

Cytomegalovirus (CMV) Pneumonia with Organizing Pneumonia▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest CT demonstrates diffuse, confluent, geographic ground-glass opacities without a clear zonal distribution, though showing mild upper and mid-lung predominance. Right middle lobe biopsy confirmed cytomegalovirus (CMV) pneumonia with secondary organizing pneumonia and focal features of aspiration.

Key takeaways

Cytomegalovirus (CMV) pneumonia can present with extensive ground-glass opacities and can trigger a prominent secondary organizing pneumonia response. Although typically seen in severely immunocompromised individuals, severe and extensive presentations can occasionally occur in patients without a previously known history of immune suppression.

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