CTICasesLow-Grade Marginal Zone B-Cell Lymphoma
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Imaging findings
Chest radiograph and CT show a slowly growing, solitary, nonsegmental, lobulated mass-like opacity in the right suhilar lung. Contrast-enhanced CT reveals that pulmonary vessels and patent, distorted airways run directly through the lesion without being occluded. PET/CT demonstrates moderate FDG avidity of the lesion. Following radiation therapy, subsequent imaging shows findings of acute radiation pneumonitis in the treated region.
Key takeaways
Primary pulmonary lymphoma, most commonly low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), characteristically presents as a solitary or slowly growing mass that preserves underlying bronchovascular architecture, allowing patent airways and vessels to traverse the lesion. These indolent tumors are highly radiosensitive and can be managed effectively with localized radiation therapy if systemic disease is absent.
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