CTICasesEsophageal Leiomyoma
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Imaging findings
A chest and pelvis CT incidentally revealed eccentric, lobulated soft tissue thickening in the esophagus with chunky intraluminal calcifications. No obvious surrounding lymphadenopathy was noted. Biopsy and immunohistochemical staining confirmed leiomyoma (SMA positive, CK negative).
Key takeaways
Esophageal leiomyomas are common benign mesenchymal tumors. Calcification can be a feature, reportedly seen in up to one-third of cases. Differential considerations for calcified esophageal masses include GIST, carcinoid, or hemangiomas, but immunohistochemistry can help confirm the diagnosis of leiomyoma.
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