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Cystic Metastasis from Skin Cancer (Angiosarcoma / Basal and Squamous Cell Carcinoma)

Cystic Metastasis from Skin Cancer (Angiosarcoma / Basal and Squamous Cell Carcinoma)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph shows bilateral pneumothoraces. CT reveals multiple bilateral thin-walled cysts with varying wall thickness, some with air-fluid levels, and associated nodules. There are also confluent opacities in lung bases and pleural effusions. One case shows a few nodules and mostly cysts, one with an air-fluid level.

Key takeaways

Cystic lung lesions and recurrent pneumothoraces in a patient with a history of skin malignancy (especially angiosarcoma, but also aggressive basal/squamous cell carcinoma) can be indicative of metastatic disease, even with minimal or no solid components to the cysts. Angiosarcoma, particularly, is known for cystic metastases. The exact diagnosis may require biopsy.

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