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T-Cell Lymphoma with Perivascular and Mediastinal Infiltration

T-Cell Lymphoma with Perivascular and Mediastinal Infiltration▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT shows extensive soft tissue encasing the pulmonary artery and infiltrating the aortopulmonary window and right paratracheal region. There is also a pericardial effusion. Lung windows show consolidation around the bronchovascular bundles in the right middle lobe, with a ground-glass appearance.

Key takeaways

Lymphoma, despite being a 'soft tissue' tumor, can aggressively infiltrate vessels and mediastinal structures, and cause pericardial effusion. This appearance, especially with an aggressive presentation and pancytopenia, suggests lymphoma/leukemia invasion, potentially mimicking severe infection but favored over infection in this clinical context.

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