CTICasesCLL with Pleural Infiltration and Extrapleural Spread
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Imaging findings
Chest radiograph showed a large amount of pleural fluid in the basal hemithorax. CT revealed extensive intrathoracic lymph node enlargement consistent with CLL, along with significant pleural fluid and marked pleural membrane thickening, including a thick rind of tissue trapping the right lung. Abnormal tissue growth was observed in the extrapleural fat.
Key takeaways
This case demonstrates an unusual and extensive presentation of Chronic Lymphocytic Leukemia (CLL) with direct tumor infiltration of the pleural surfaces and extrapleural fat, rather than just a reactive effusion. Pathology confirmed substantial infiltration of the pleural surface by lymphocytes, highlighting a rare form of tumor involvement beyond typical lymphadenopathy.
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