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Benign Metastasizing Leiomyoma to the Lung

Imaging findings

Multiple longstanding, large, smooth, and somewhat bizarrely configured basal lung nodules are present, with low attenuation centers, and have been stable since 2008. These lesions also demonstrate low attenuation on mediastinal window settings, appearing almost myxoid. Biopsy confirmed the lesions as leiomyomas.

Key takeaways

This patient had complicated uterine surgeries years prior for large leiomyomas, with intravascular/intravenous components. Benign metastasizing leiomyoma to the lung typically occurs in patients with a history of uterine leiomyomas, where surgical manipulation is thought to facilitate the dissemination of tumor cells into the venous system. These lesions are generally stable over long periods.

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