CTICases ← All cases

Mediastinal Metastasis from Breast Cancer simulating Thymic Rebound

Mediastinal Metastasis from Breast Cancer simulating Thymic Rebound▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT reveals extensive soft tissue anterior to the aorta in the mediastinum, with adjacent destruction of the upper sternum. MRI with in-phase and out-of-phase imaging shows no signal dropout within the mediastinal soft tissue, indicating a lack of fat.

Key takeaways

Chemical shift ratio imaging (in/out of phase MRI) can be a helpful technique to differentiate mediastinal soft tissue, as lack of signal dropout suggests a non-fatty mass, such as metastasis, rather than thymic rebound or hyperplasia. Local spread of breast cancer through the internal mammary chain can present as mediastinal soft tissue and sternal involvement.

AI-assisted summary — may contain errors. Verify against the source video. Learn more

More from this webinar

See all cases from June 2, 2016 →

Related Neoplastic cases

Browse all Neoplastic cases →