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Mucinous Adenocarcinoma

Imaging findings

Chest radiograph shows a left lower lung consolidative opacity mimicking pneumonia. Contrast-enhanced chest CT demonstrates a focal consolidative mass in the left lower lobe containing multiple small cystic spaces and internal air bronchograms. Numerous separate, satellite ground-glass and consolidative nodules with central cavitation (pseudo-cavitation) are present throughout the left lower lobe.

Key takeaways

Invasive mucinous adenocarcinoma (formerly mucinous BAC) of the lung characteristically presents as a persistent consolidation or lobar pneumonia-like process that fails to resolve with antibiotics. Multi-centricity or satellite nodules in the same lobe represent aerogenous (airway) dissemination of tumor cells carried in mucinous secretions, which typically harbor KRAS mutations.

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