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Clavicular Metastasis of Osteosarcoma

Imaging findings

Serial chest radiographs in a young woman with a history of lower extremity osteosarcoma show progressive sclerosis and remodeling of the medial right clavicle. CT confirms a destructive, osteosarcoma metastasis in the medial clavicle. A follow-up radiograph demonstrates surgical absence of the medial clavicle following resection.

Key takeaways

While osteosarcoma metastases are overwhelmingly hematogenous to the lungs, skeletal-to-skeletal metastases can occur. A new osteolytic or sclerotic lesion in the clavicle of a patient with prior osteosarcoma represents metastatic disease. Resection of the clavicle (claviculectomy) is performed for oncological control and symptom relief.

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