CTICasesThymoma
Imaging findings
Chest CT in a patient with a history of head and neck cancer shows multiple pleural-based soft-tissue nodules in the left hemithorax, with a small nodule in the right hemithorax. There is complete absence of a primary anterior mediastinal thymic mass. Biopsy of a pleural nodule confirms type B1 thymoma.
Key takeaways
Thymomas are epithelial neoplasms that typically arise in the anterior mediastinum. Rarely, they can occur in ectopic locations, including the pleura, arising from displaced thymic remnants. Multiple pleural thymoma nodules in the absence of a primary mediastinal mass can represent either primary ectopic pleural thymomas with pleural dissemination (drop metastases) or an occult mediastinal primary that has regressed.
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