CTICasesExcipient lung disease
Imaging findings
Chest CT shows diffuse, tiny, miliary-like centrilobular nodules in a random distribution without pleural or fissural involvement. Biopsy confirmed numerous intravascular and interstitial foreign-body granulomas containing birefringent crystals.
Key takeaways
Excipient lung disease occurs from the intravenous injection of crushed oral tablets. Insoluble tablet binders (such as talc or microcrystalline cellulose) lodge in the pulmonary microcirculation, causing foreign-body granulomas, diffuse miliary nodules on CT, and progressive pulmonary hypertension.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- SchwannomaNeoplastic
- ThymomaNeoplastic
- Shared-sheath hematomaIatrogenic
- Acute eosinophilic pneumoniaExposure
- Malpositioned patent ductus arteriosus closure deviceIatrogenic
- Mixed connective tissue disease-associated non-specific interstitial pneumoniaILD
- Metastatic melanomaNeoplastic
- Sinus venosus atrial septal defectCongenital
See all cases from October 11, 2018 →