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End-Stage Sarcoidosis with Anterior Pneumothorax

Imaging findings

Chest CT and radiograph show end-stage sarcoidosis characterized by upper-lobe predominant fibrosis, paracicatricial emphysema, and retraction of the hila. In the setting of recurrent pneumothoraces and prior pleurodesis, a repeat radiograph shows a dramatic leftward deviation of the anterior junction line, which CT confirms is caused by a large, localized anterior pneumothorax tracking into a specific pocket of the pleura where it is not restricted by adhesions.

Key takeaways

In patients with end-stage fibrotic lung disease who have had prior pleurodesis, recurrent pneumothoraces may not present with classic pleural lines due to extensive pleural adhesions. Instead, pleural air can collect in isolated pockets, such as the anterior mediastinum, leading to severe deviation of normal radiographic landmarks like the anterior junction line.

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