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Light-Chain Deposition Disease

Imaging findings

Chest CT shows multiple discrete pulmonary cysts, some associated with vascular structures, in a patient with Sjögren's syndrome and light-chain deposition disease (LCDD).

Key takeaways

Light-chain deposition disease (LCDD) associated with Sjögren's syndrome can present with diffuse cystic lung disease. The cysts are thought to result from light-chain deposition in bronchial walls leading to small airway dilatation.

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