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Pleural Sarcoidosis

Imaging findings

Serial chest CTs show a chronic right pleural effusion and nodular/lobulated pleural thickening, associated with classic lung parenchymal perilymphatic nodularity. Pleural biopsy confirmed non-necrotizing granulomas of sarcoidosis in a patient with CLL.

Key takeaways

Pleural involvement is a rare manifestation of sarcoidosis, occurring in less than 1% of patients. It presents as an exudative effusion and pleural thickening, which must be histologically differentiated from lymphoma or tuberculosis.

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