CTICasesCVID-Associated GLILD
Imaging findings
Chest CT in a patient with common variable immunodeficiency (CVID) shows diffuse, perilymphatic/stellate pulmonary nodules, mediastinal lymphadenopathy, and splenomegaly. Biopsy confirmed granulomatous-lymphocytic interstitial lung disease (GLILD). The lesions resolved completely after immunosuppressive therapy.
Key takeaways
GLILD is a rare, non-infectious pulmonary complication of CVID characterized by granulomatous and lymphocytic infiltration. It responds well to combination chemotherapy/immunosuppressants (e.g., rituximab and mycophenolate).
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