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Straight Edge Sign in CTD-ILD

Imaging findings

CT chest shows bilateral basal-predominant pulmonary fibrosis with a sharp, horizontal, straight-line transition from normal lung to confluent fibrosis at the diaphragmatic interface, representing the 'straight edge sign'.

Key takeaways

The 'straight edge sign' is a highly specific feature of connective tissue disease-associated interstitial lung disease (CTD-ILD, particularly systemic sclerosis or rheumatoid arthritis). It represents a sharp boundary of fibrosis that is not typically seen in idiopathic pulmonary fibrosis (IPF/UIP).

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