Lymphatic Pearls in Catastrophic Antiphospholipid Antibody Syndrome with Renal Failure
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Imaging findings
Diffuse, extensive, bilateral lung opacities, appearing confluent and consolidative on chest radiograph. CT shows interstitial lung edema with round or oval-shaped opacities along interlobular septa, described as "lymphatic pearls," along with other signs of interstitial edema and bilateral pleural fluid. The appearance improved the following day after plasmapheresis.
Key takeaways
This case illustrates a beautiful example of "lymphatic pearls" on CT, a rare finding in interstitial lung edema speculated to represent distended lymphatics. This specific presentation was observed in a patient with catastrophic antiphospholipid antibody syndrome and renal failure, a known association.
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