CTICasesMediastinal paraganglioma with SSTR avidity
Imaging findings
CT shows a massive, vascular anterior mediastinal mass with peripheral enhancement and central necrosis. Gallium-68 DOTATATE scan demonstrates intense receptor-mediated tracer uptake at the enhancing periphery.
Key takeaways
Mediastinal paragangliomas are highly vascular neuroendocrine tumors. Because they express somatostatin receptors (SSTR), PET/CT with SSTR analogs (such as Ga-68 DOTATATE) is highly sensitive for staging and confirmation. Surgical resection is associated with severe bleeding risk.
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