CTICasesLangerhans cell histiocytosis (LCH) involving the thyroid and lungs
Imaging findings
CT scan shows a large, enhancing thyroid mass, a sellar region mass, and scattered lower-lobe predominant pulmonary nodules and bizarre cysts in a non-smoking female.
Key takeaways
While pulmonary LCH is classically smoking-related and upper-lobe predominant, systemic LCH can cause hematogenous seeding of Langerhans cells, presenting with lower-lobe predominant cysts/nodules alongside extrathoracic lesions (e.g., thyroid or sellar masses).
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