CTICasesHantavirus Pulmonary Syndrome
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Imaging findings
Initial chest radiograph shows reticular-nodular opacities and air-space disease, predominant mid-lungs and bases. A few hours later, worsening appearance with more consolidation. CT shows diffuse centrilobular ground-glass opacities, worsening towards the bases, with areas of consolidation and prominent interlobular septal thickening (interstitial edema), peribronchial fluid cuffs, subpleural edema, and small pleural effusions.
Key takeaways
Hantavirus Pulmonary Syndrome (HPS) is a rapidly progressive pulmonary edema caused by exposure to rodent droppings, carrying a high mortality. Imaging features include diffuse ground-glass opacities, consolidation, and interstitial edema, predominantly in the mid-lungs and bases. It is a zoonotic disease.
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