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Progressive Basilar LIP Cysts

Imaging findings

Chest CT demonstrates progressive, extensive, and irregular cystic changes predominant in the lower lung zones over an 8-year period in a patient with Sjögren's syndrome and lupus overlap, representing progressive LIP.

Key takeaways

LIP-associated pulmonary cysts can demonstrate marked progression over several years in patients with systemic autoimmune disorders, frequently showing a basilar predominance unlike Langerhans cell histiocytosis.

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