CTICasesGranulomatous-Lymphocytic Interstitial Lung Disease (GLILD) in CVID
Imaging findings
Chest radiograph and chest CT demonstrate bilateral, ill-defined basal-predominant lung nodules, septal lines, and larger consolidative abnormalities. Soft tissue windows reveal prominent mediastinal and hilar lymphadenopathy with a sarcoid-like distribution.
Key takeaways
Granulomatous-lymphocytic interstitial lung disease is a rare interstitial lung disease associated with common variable immunodeficiency. Biopsy is typically required to confirm the presence of granulomas and lymphocytic infiltration, which characteristically present with basal-predominant nodules and sarcoid-like lymphadenopathy.
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