CTICasesAdenocarcinoma Spectrum (Preinvasive and Invasive Components)
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
Initial CT showed multifocal, partially consolidated, peribronchial airspace disease in the right lung, alongside an "angry-looking" nodule (two confluent, mildly spiculated nodules with lobulated borders). Follow-up CT 3-4 months later revealed resolution of the airspace disease but new peribronchial ground-glass lesions (some with air bronchograms, suggestive of low-grade preinvasive adenocarcinoma), and an increase in size of the original nodule. PET/CT showed an SUV of 4.9 in the nodule, with no lymph node involvement.
Key takeaways
Persistent or growing nodules, especially with spiculated or lobulated borders, and new ground-glass lesions with air bronchograms, should raise high suspicion for adenocarcinoma spectrum, even in the presence of resolving inflammatory disease. The radiographic finding of pseudocavitation in a nodule increases the likelihood of lepidic growth and adenocarcinoma.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Arterial Central Venous Catheter Placement (into aorta) via IJ and Subclavian VeinIatrogenic
- Retained Suction Catheter Tip (Intraoperative Foreign Body)Iatrogenic
- Choriocarcinoma with Hemorrhagic Pulmonary MetastasesNeoplastic
- Anomalous Left Coronary Artery from Pulmonary Artery (ALCAPA) with Proximal Interruption of the Right Pulmonary ArteryCongenital
- Hypertrophic Cardiomyopathy (HCM)Congenital
- Loeffler's Endocarditis (Fibrotic Phase)Inflammatory
- Unilateral Acute Respiratory Distress Syndrome (ARDS) due to Left Pulmonary Artery AgenesisCongenital
- Aberrant Right Subclavian ArteryCongenital
See all cases from August 14, 2015 →
Related Neoplastic cases
- Recurrent Squamous Cell Carcinoma in Respiratory Papillomatosis with Rib Invasion
- Ectopic Mediastinal Parathyroid Adenoma
- Post-Transplant Lymphoproliferative Disorder (PTLD) Presenting as Airway-Centric Lung Nodules
- Adult Tracheal Papillomatosis
- Diffuse Multifocal Pulmonary Adenocarcinoma with Lepidic Growth
- Intrapulmonary Solitary Fibrous Tumor with Cystic Changes