Pulmonary Mucormycosis in a Diabetic
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Imaging findings
Serial chest radiographs show the rapid development of a large, mass-like consolidation in the right upper lobe, which undergoes central cavitation over several days. Chest CT demonstrates a thick-walled cavitary mass with surrounding extensive ground-glass opacity. Bronchoscopy and bronchoalveolar lavage (BAL) grew Rhizopus.
Key takeaways
Pulmonary mucormycosis (caused by zygomycetes such as Rhizopus or Mucor) is an aggressive, angioinvasive fungal infection. While most commonly seen in severely neutropenic or leukemic patients, it can also occur in poorly controlled diabetic patients. The infection manifests as rapid consolidation, mass-like lesions, and cavitation, and requires urgent treatment with surgical debridement and appropriate systemic antifungals (e.g., amphotericin B or isavuconazole).
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