CTICasesSarcoidosis Presenting as Emphysema in a Non-Smoker
Imaging findings
CT reveals upper lobe predominant emphysema, architectural distortion, paraseptal emphysema, and centrilobular emphysema, with distorted fissures. Additionally, ground glass opacities are noted in the lower lobes, accompanied by traction bronchiectasis and bronchiolectasis.
Key takeaways
This case highlights an atypical presentation of sarcoidosis, appearing almost entirely as emphysema in a non-smoker. The diagnosis was confirmed by open lung biopsy, showing non-necrotizing granulomas alongside emphysema spaces and fibrosis. The discussion explores whether this is a true sarcoid presentation or a granulomatous response to another underlying pathology.
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