CTICasesPazopanib-Induced Large Vessel Vasculitis
Imaging findings
CT chest and abdomen demonstrate new, eccentric wall thickening and narrowing of the subclavian, brachiocephalic, aortic, and right renal arteries in a patient with renal cell carcinoma on the tyrosine kinase inhibitor Pazopanib.
Key takeaways
Pazopanib is a multi-targeted tyrosine kinase inhibitor (not a TNF-alpha inhibitor). It has been associated with drug-induced vasculitis, which can affect large and medium-sized vessels. Recognizing this drug-induced etiology is crucial as discontinuation of the drug and steroid therapy can reverse the vasculitis.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Septic Lakes in Interstitial Pulmonary EdemaVascular
- Scleroderma-Rheumatoid Arthritis Overlap with UIPAutoimmune
- Anti-Jo-1 Anti-Synthetase Syndrome Interstitial Lung DiseaseAutoimmune
- Benign Metastasizing LeiomyomaNeoplastic
- DIPNECH with Carcinoid TumorletsNeoplastic
- Metastatic Paraganglioma Mimicking DIPNECHNeoplastic
- Syphilitic Aortitis (Historical Cases)Infection
- Misplaced Swan-Ganz Catheter via Left Superior Intercostal VeinIatrogenic
See all cases from April 30, 2020 →