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Fibrotic Hypersensitivity Pneumonitis

Fibrotic Hypersensitivity Pneumonitis▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Radiographs show diffuse fibrosis in both upper and lower lobes, with peripheral and peribronchovascular distribution. Thin-cut CT images demonstrate reticulation, honeycombing, traction bronchiectasis, and a background of mosaic attenuation. Expiratory images confirm areas of air trapping, with prominent upper lobe fibrosis.

Key takeaways

Fibrotic hypersensitivity pneumonitis (HP) combines features of interstitial fibrosis (reticulation, honeycombing, traction bronchiectasis) and small airway disease (mosaic attenuation, air trapping). Differentiation from IPF is crucial, with upper lobe involvement and air trapping being key distinguishing features. Prognosis is worse if the inciting antigen cannot be identified.

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