CTICasesDaptomycin-Induced Organizing Pneumonia
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Imaging findings
Chest CT shows bilateral, peripheral, non-segmental ground-glass opacities and areas of consolidation with subtle perilobular arcading and bronchovascular distribution, primarily involving the upper lobes.
Key takeaways
Daptomycin-induced acute lung injury is a well-recognized drug reaction that typically manifests as eosinophilic pneumonia or an organizing pneumonia pattern. Recognition of the characteristic peripheral and bronchocentric ground-glass/consolidative distribution, coupled with a history of daptomycin therapy and prompt clinical resolution upon drug discontinuation, is essential to avoid misdiagnosis as infectious pneumonia.
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