CTICasesCellular nonspecific interstitial pneumonia (NSIP)
Imaging findings
CT scan shows progressive, lower-lobe predominant, symmetric, confluent ground-glass opacities without significant traction bronchiectasis or honeycombing. Lung biopsy confirmed cellular NSIP with interstitial lymphocytic infiltration.
Key takeaways
Cellular NSIP is characterized by diffuse ground-glass opacities without significant fibrotic markers (such as traction bronchiectasis). It is frequently associated with connective tissue diseases (e.g., scleroderma or Sjögren's) and is highly steroid-responsive.
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