CTICasesGranulomatous-Lymphocytic Interstitial Lung Disease (GLILD) with Obstructive Small Airways Disease in CVID
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
A patient with Common Variable Immunodeficiency (CVID) and Granulomatous-Lymphocytic Interstitial Lung Disease (GLILD). CT imaging showed mosaic attenuation and peripheral reticulation. Expiration series confirmed substantial air trapping within the lobules, indicating obstructive small airways disease. Open lung biopsy pathology revealed prominent peribronchiolar lymphoid hyperplasia with lymphocytic aggregates surrounding distal airways.
Key takeaways
This is an interesting example of GLILD in CVID, presenting with a prominent obstructive small airways component manifested as mosaic attenuation and air trapping. The pathological correlation confirmed peribronchiolar lymphoid hyperplasia, providing a clear explanation for the small airways obstruction. This case highlights GLILD as a differential diagnosis for obstructive small airways disease.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Granulomatosis with Polyangiitis (GPA) Presenting as Mass-Like ConsolidationAutoimmune
- Relapsing PolychondritisAutoimmune
- Pulmonary Vein Stenosis Post-Ablation with CollateralsIatrogenic
- Sinus of Valsalva AneurysmCongenital
- Pulmonary Artery Compression of Right Middle Lobe Bronchus in Eisenmenger SyndromeVascular
- Pulmonary Amyloidosis with Hemorrhage into CystsMetabolic
- Lymphocytic Interstitial Pneumonia (LIP) in Sjögren SyndromeILD
- Isolated Cardiac Sarcoidosis with Ventricular TachycardiaAutoimmune
See all cases from March 11, 2015 →