CTICasesPolymyositis-Associated Interstitial Lung Disease (NSIP / Organizing Pneumonia Overlap)
▶ Watch on YouTube — age-restricted, cannot embed here
Imaging findings
Chest CT shows multifocal subpleural and peripheral ground-glass opacities with classic subpleural sparing, transitioning into a geographic, peribronchovascular distribution of consolidation in the lung bases. These findings represent a mixed pattern of non-specific interstitial pneumonia (NSIP) and organizing pneumonia (OP).
Key takeaways
Interstitial lung disease is highly associated with polymyositis, particularly in patients harboring the anti-Jo-1 antibody, which carries up to a 70% risk of developing ILD. Serum KL-6 levels correlate with ILD severity, and the imaging frequently reveals an overlap of NSIP and organizing pneumonia patterns.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Patent Ductus Arteriosus (PDA) and Necrotizing Enterocolitis (NEC)Congenital
- 180-Degree Flip of a Defibrillator along the Long AxisIatrogenic
- Daptomycin-Induced Pulmonary ToxicityILD
- Strongyloides Hyperinfection SyndromeInfection
- Cytomegalovirus (CMV) Pneumonia with Organizing PneumoniaInfection
- Typical Type A Acute Aortic DissectionVascular
- Type A Aortic Dissection with Retrograde Valve Prolapse and Intimal IntussusceptionVascular
- Atrial Extension of Mitral Annular Calcification (MAC)Metabolic
See all cases from November 23, 2014 →
Related ILD cases
- Acute Fibrinous Organizing Pneumonia
- Cryptogenic Organizing Pneumonia
- Antisynthetase Syndrome with Organizing Pneumonia and Interstitial Lung Disease
- Chronic Hypersensitivity Pneumonitis
- Chronic Lung Allograft Dysfunction with Pleuroparenchymal Fibroelastosis and Bronchiolitis Obliterans
- Chronic Hypersensitivity Pneumonitis (Progression with Loss of Air Trapping)