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Dendriform Pulmonary Ossification

Imaging findings

A muscular 47-year-old man's chest radiograph shows subtle fine reticular opacities in the lower lobes, initially misinterpreted elsewhere as infection. CT shows dense, chronic-appearing calcified and ossified branching structures arrayed along the interlobular septa in both lower lobes, without associated fibrosis or other chronic lung disease.

Key takeaways

Branching, septally distributed calcified/ossified structures without underlying fibrosis, aspiration, or other chronic lung disease represent dendriform pulmonary ossification, an idiopathic entity that can mimic chronic infection on radiographs but should be recognized by its dense, chronic, branching calcified appearance on CT rather than pursued as an acute infectious process.

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