CTICasesMetastatic Pulmonary Calcification
Imaging findings
CT chest in a post-transplant patient with chronic renal failure shows progressive, symmetric, centrilobular ground-glass nodules and dense, calcified nodular consolidation predominantly distributed in the upper lobes of the lungs.
Key takeaways
Metastatic pulmonary calcification is a metabolic disorder characterized by calcium deposition in normal lung tissue, typically in patients with chronic renal failure or hyperparathyroidism. The calcification is characteristically upper-lobe-predominant because the higher alveolar pH in the apices (due to relative hyperventilation and CO2 removal) promotes calcium precipitation.
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