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Pericardial fat necrosis

Imaging findings

Chest CT and PET-CT show an area of inflammatory fat stranding in the right anterior cardiophrenic fat pad with mild FDG avidity, associated with an ipsilateral pleural effusion.

Key takeaways

Pericardial fat necrosis is a benign, self-limiting cause of acute chest pain, classically presenting as a focus of fat stranding within the cardiophrenic fat pad. It is frequently accompanied by a small ipsilateral pleural effusion, which should not be mistaken for malignancy or infection.

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