Disseminated Cryptococcus neoformans infection
Imaging findings
Chest CT in a 41-year-old HIV-positive male shows unilateral pleural effusion and extensive, nodular pleural thickening and mediastinal lymphadenopathy. Pleural fluid culture and CSF grew Cryptococcus neoformans.
Key takeaways
Disseminated Cryptococcus neoformans infection in HIV/AIDS patients can present with atypical pulmonary manifestations, such as extensive nodular pleural thickening and effusion, mimicking pleural mesothelioma or metastatic disease. It resolves following antifungal treatment.
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