Persistent Cavitary Coccidioidomycosis
Imaging findings
CT chest in an HIV-positive patient shows a thick-walled cavitary lung lesion surrounded by multiple small satellite nodules. Over 16 months of follow-up and antifungal therapy, the cavity shows partial volume reduction and wall thinning but persists as a residual cavitary lesion.
Key takeaways
Coccidioidomycosis is an endemic mycosis that can present with a wide spectrum of findings. In immunocompromised patients, it commonly causes chronic cavitary pneumonia. These cavities can be highly persistent and fail to resolve completely despite adequate antifungal treatment, leaving behind residual thin-walled cavities or nodules.
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