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Shrinking Lung Syndrome in SLE

Imaging findings

CT chest in a patient with systemic lupus erythematosus (SLE) shows progressive, severe under-inflation of both lungs with elevated diaphragms and basal subsegmental atelectasis, without any evidence of parenchymal interstitial lung disease or pleural effusion.

Key takeaways

Shrinking lung syndrome is a rare manifestation of SLE, characterized by progressive restrictive lung volumes, elevated diaphragms, and diaphragmatic weakness. Radiologically, the lung parenchyma appears normal apart from compressive atelectasis at the bases, and the diagnosis is confirmed by restrictive pulmonary function tests.

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