Diffuse Alveolar Hemorrhage
Imaging findings
Chest CT in a post-bone marrow transplant patient shows diffuse, ground-glass opacities and airspace consolidation with pleural effusions. Sequential aliquots from bronchoalveolar lavage return fluid that becomes progressively more hemorrhagic.
Key takeaways
Diffuse alveolar hemorrhage is a highly lethal non-infectious pulmonary complication in hematopoietic stem cell transplant recipients. The diagnosis is confirmed bronchoscopically when sequential bronchoalveolar lavage aliquots yield progressively bloodier fluid, and imaging typically shows non-specific ground-glass opacities and consolidation.
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