CTICasesRecurrent Secretory Carcinoma of the Breast (Initially Diagnosed at Age 11) with Rapid Response to Chemotherapy
Imaging findings
Initially, a left infra-hilar mass causing left lower lobe collapse and volume loss is seen, along with perilymphatic disease in the right lung. Over one month, this progressed to widespread lymphangitic carcinomatosis throughout the right hemithorax and an enlarging mass obstructing the left lower lobe bronchus. Subsequent imaging after chemotherapy showed near-complete resolution of all disease.
Key takeaways
This case is remarkable for its presentation of secretory carcinoma of the breast (a rare type) with initial diagnosis at the exceptionally young age of 11, followed by a 20-year disease-free interval before recurrence. The widespread metastatic disease responded dramatically to experimental chemotherapy within a month, demonstrating the sensitivity of this specific tumor type to treatment despite its triple-negative nature.
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