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Acute ARDS from Blastomycosis

Imaging findings

CT in a 20-year-old healthy female shows extensive consolidation, multiple small nodules, and a pleural effusion, progressing rapidly to full-blown acute respiratory distress syndrome (ARDS) from Blastomycosis.

Key takeaways

Blastomycosis is a dimorphic fungus endemic to the Ohio and Mississippi River valleys. While it typically causes chronic pneumonia, it can present in young, immunocompetent hosts as an acute, severe ARDS requiring mechanical ventilation or ECME.

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